Positive displacement pipettes are specialized liquid-handling instruments designed for accurate dispensing of viscous, volatile, or dense liquids that are difficult to handle with air-displacement pipettes. They use disposable piston–capillary tip systems, where the piston directly contacts the liquid, eliminating air gaps and ensuring precise volume delivery.
These pipettes are widely used in molecular biology, pharmaceutical, chemical, and clinical laboratories for applications involving oils, solvents, or highly concentrated solutions.