Positive displacement pipettes are specialized liquid handling instruments designed for the accurate dispensing of viscous, volatile, or dense liquids that are difficult to handle with standard air-displacement pipettes. Unlike conventional pipettes, they use a piston that comes into direct contact with the liquid inside a disposable capillary and piston tip, eliminating air gaps and ensuring precise volume transfer regardless of liquid properties.
These pipettes are particularly useful for PCR, molecular biology, pharmaceutical, and chemical applications, where accuracy and reproducibility are critical, even with challenging samples.