Neoprene is a versatile synthetic rubber material, technically known as polychloroprene, that is widely used in textiles and laminates for its unique combination of flexibility, insulation, and water resistance. Neoprene fabric is typically made by sandwiching a sheet of neoprene foam between layers of fabric (such as nylon, polyester, or spandex) to create a soft, durable, and stretchy composite material.